Error code 0x80070643 on windows normally occurs when updating or installing an application. Cure it by running the Windows Update Troubleshooter, restarting the windows installer service, repairing system files with sfc /scannow, updating or reinstalling the .NET Framework and temporarily disabling 3 rd party antivirus software and then again trying to run the update.
You can fix Windows error 0x80070643 by restarting your PC, running Windows Update troubleshooter, repairing or reinstalling the affected app, updating .NET Framework, and installing pending Windows updates.