NYT Connections with NFL players is just like the normal game: locate four sets of four related items out of the 16 words, but the topics are football, related, for example, team home cities, retired stadiums, or player nicknames/stats, thus a combination of general knowledge and deep NFL expertise is required to identify the common threads and tricky wordplay.
It uses color-coded categories (yellow, green, blue, purple) for difficulty, with yellow being easiest and purple hardest, raising the level of difficulty through synonyms, cultural references, and abstract links, thus players have to switch across the skills while playing the game.