In order to resolve the League of Legends Vanguard error VAN 57, restarting your computer and the Riot Client is the first thing to do. If that doesn’t help, go for a thorough reinstallation by deleting Riot Vanguard, League of Legends, and associated processes, then installing both again which will bring back Vanguard. If the issue still exists, you might have to look into the BIOS of your computer for settings such as Secure Boot and TPM, or raise a support ticket.