If I were you, I’d mainly check VRM quality and power delivery first especially if you plan to use a 13th- or 14th-gen chip and maybe overclock. A weak VRM means unstable voltage, higher temps, and possible throttling under load. After that, DDR5 support + good board BIOS/firmware support matter a lot (some manufacturers give more frequent updates than others). If your build is fairly standard (gaming or productivity, no crazy overclock), you don’t need PCIe 5.0 just yet but it’s nice “future-proofing,” especially if you plan to use next-gen GPUs or SSDs later.